| Advancing oral health: the antimicrobial power of inorganic nanoparticles |
Dai‑Hwan Kim1, Junseok Kim1, Chae Yeon Lee1, Min‑Ho Hong2
, Jun Hyuk Heo1,3
, Jung Heon Lee1,3,4,5,6
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1School of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea
2Department of Dental Biomaterials and Research Institute of Oral Science, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, Republic of Korea
3Research Center for Advanced Materials Technology, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea
4Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea
5Institute of Quantum Biophysics (IQB), Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea
6Department of MetaBioHealth, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea |
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Received: September 25, 2023; Revised: November 23, 2023 Accepted: December 6, 2023. Published online: January 16, 2024.
*Dai‑Hwan Kim and Junseok Kim contributed equally to this work. |
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| ABSTRACT |
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Oral health is vital to overall well-being, with the human mouth being home to a myriad of microorganisms. Plaque biofilms, predominantly responsible for dental cavities, consist of diverse bacteria and fungi. These biofilms can lead to oral diseases, such as dental caries and periodontal diseases. In recent times, the spotlight has shifted to inorganic nanoparticles (NPs) as potential dental materials, attributed to their potent antibacterial properties which arise from their expansive-specific area, heightened charge density, and catalytic features. This review aims to explore the antimicrobial efficacy of inorganic NPs, discussing the range of oral diseases they combat and their underlying antibacterial mechanisms. Furthermore, it highlights the distinctive characteristics and applications of various inorganic NPs, with a particular emphasis on metal oxides and calcium phosphates. The review concludes by considering future prospects and developments in the realm of antibacterial inorganic NPs. |
| Key words:
Ceramic · Nanoparticle · Antibacterial · Oral · Biofilms · Antifouling |
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