| The structural and bioactive behaviour of strontium‑doped titanium dioxide nanorods |
Rinmayee Praharaj1,2, Snigdha Mishra1, Tapash R. Rautray2
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1Dept. of Physics, Berhampur University, Bhanja Bihar, Berhampur, Odisha 760007, India
2Biomaterials and Tissue Regeneration Laboratory, Centre of Excellence in Theoretical and Mathematical Sciences, Siksha ‘O’ Anusandhan University, Khandagiri Square, Bhubaneswar, Odisha 751030, India |
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Received: November 15, 2019; Revised: November 30, 2019 Accepted: December 6, 2019. Published online: March 31, 2020. |
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| ABSTRACT |
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In the present work, various concentrations of strontium ions loaded titanium dioxide nanorods and common titanium dioxide nanorods (control) were synthesized by electrochemical anodization technique to get the implant with superior bioactivity. Cell viability and antibacterial efficacy studies were estimated using MTT assay and solid agar medium. The characterisation results confirmed that Sr2+ was successfully incorporated into TiO2 nanorods. Compared with common TiO2 nanorods (control), Sr2+ loaded TiO2 nanorods showed higher surface roughness, adhesion strength, and water wetting angle. MTT assay showed better cell response on Sr-TiO2 nanorod surface as compared to control and the antibacterial test showed that Sr2+ loaded TiO2 nanorods have superior antibacterial activity against pathogenic bacterial strain E. coli and S. aureus. Sr2+ incorporated TiO2 nanorod arrays can be used as a potential candidate for hard tissue implant applications. |
| Key words:
Titanium dioxide · Nanorods · Strontium · Bioactivity |
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